These are diseases like sickle cell anemia or beta thalassemia.

比如镰状细胞性贫血或β贫血。

To prevent complications from an existing blood or bleeding disorder, such as sickle cell disease, thalassemia, or anaemia caused by kidney disease, haemophilia, or von Willebrand disease.

预防现有血液或出血性疾病的并，如镰状细胞病、贫血或由肾脏疾病、血友病或血管性血友病引起的贫血。

Usually, patients with mild thalassemia don't need treatment, while patients with severe thalassemia are treated with blood transfusions.

通常情况下，轻度贫血无需治疗，而重度贫患者需输血治疗。

Thalassemia is a group of inherited blood disorders.

贫血是一组遗传性血液疾病。

And alpha thalassemia is caused by mutations in the alpha genes, most commonly a gene deletion.

而α贫血是由α基因变异引起的，最常见的原因是基因缺失。

The initial symptoms of minor and moderate alpha thalassemia are due to anemia, which include pallor, shortness of breath, and easy fatigability.

轻度和度α贫血的状往往是贫血，表现为苍白、气促、乏力。

If a person has two defective alpha genes, the person has alpha thalassemia minor, which causes mild symptoms.

如果有2个α基因异常，则会出现轻度α贫血，会引起轻微的状。

All right, as a quick recap: alpha thalassemia is an autosomal recessive disorder caused by deletion of alpha globin genes on chromosome 16.

得！快速回顾一下：α贫血是一种常染色体隐性遗传病，由16号染色体上的α珠蛋白基因缺陷引起。

With moderate alpha thalassemia, there may be golf-ball like RBCs, due to precipitated HbH molecules.

度α贫血患者，由于HbH分子沉积，可见高尔夫球样红细胞。

So all of a sudden, if you put in, you try to fix thalassemia or sickle cell, but you end up causing like some massive vulnerability to Ebola, whatever, I'm making it up.

所以突然之间， 如果你尝试修复贫血或镰刀型细胞贫血，结果却导致了某种对埃博拉病毒的极大易感性，我是随便举个例子。

The following year, Vertex and Crispr Therapeutics, pharmaceutical companies based in Boston, Massachusetts, and Zug, Switzerland, said they would co-develop a treatment named CTX001, a treatment for two disorders: sickle-cell disease and beta thalassemia.

次年，总部位于马萨诸塞州波士顿的制药公司Vertex和总部位于瑞士楚格的Crispr Therapeutics表示，他们将共同开一种名为CTX001的治疗方法，用于治疗镰状细胞病和β贫血。

But saying like, okay, you like, I can't remember, I think it's thalassemia.

但是说到像，好吧，你像，我记不住了，我觉得是贫血。

So Greeks have to get tested before they get married and have kids to see if they both carry the gene for thalassemia, because it's devastating and kills the kid.

因此， 希腊人在结婚生子前必须接受检测， 以确定双方是否携带贫血基因，因为这种疾病极具破坏性且会危及孩子的生命。