Soft tissue sarcomas are a highly heterogeneous and polygenous group of tumor, and characterized by specific chromosome translocations and corresponding fusion genes.
From the Concept, the formation and the character of supermolecule, the author probes three basic function of supermolecule system: recognition, transformation and translocation.
With a systematic study on the effects of ionophores and ion channel on the photopotential signals, this paper verified ike nonproton ion translocation in Purple Membrane.
In this process, protein translocation machineries of the outer and inner membranes, at least three major translocase complexes, are needed to ensure the proper import of precursor proteins.
14) translocation were noted in patients with short stature, and all of these cases were found to have a specific genetic syndrome – maternal uniparental disomy (UPD) of chromosome 14.
Ewing sarcoma is associated with chromosomal mutations, specifically a translocation between the EWSR1 gene on chromosome 22 and FLI1 gene on chromosome 11.
Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.