Several clinical investigations demonstrated that intravitreous injection of plasmin before vitrectomy could reduce the risk of retinal bleeding or detachment.
Methods Three incision vitrectomy with intraocular foreign bodies extraction and retinal reattachment, endophotocoagulation, C3F8 intraocular injection and silicone oil tamponade, et al.
Examinations should include monitoring of the IOP and gonioscopy for pseudophakes and patients with prior vitrectomies to detect mechanical obstruction of the trabecular meshwork by the medication.