Arrhythmias were induced by CaCl 2(SD rats),aconitine(SD rats),ouabin(guinea-pigs) and adrenaline(rabbits)respectively Effects of Rhodiola on these arrhythmiar models were Observe.
Diester deoxyaconitine is very toxic.When deoxyaconitine was transformed into mono-ester aconitum alkaloids and lipo-alkaloids by human intestinal bacteria, the toxicity decreased.