The most commonly used method for the covalent binding of biomolecules onto 1-D nanostructures is through the diimide-activated amidation of carboxylic acid terminated nanostructures.
To turn nasal spray into meth, you’d need to first break its very strong covalent bonds, and that requires dangerous reagents and expensive, high-pressure lab equipment.
Really though, hydrogen bonds aren't chemical bonds in the same sense that ionic and covalent bonds are, but they are the strongest interactions that occur between molecules.