Methicillin and penicillin belong to the so-called " beta lactam" family of antibiotics.

甲氧西林和青霉素都属于所谓“β-胺”抗生素族。

M. pneumoniae is resistant to beta-lactam antibiotics (e.g., penicillin).

肺炎支原体对-胺类抗生素(如青霉素)具有耐药。

So, it produces beta-lactamases, which confers resistance against ampicillin and amoxicillin.

它能产生β-胺酶，从而对氨苄西林和阿莫西林产生抗。

" Staph aureus bacteria that carry these genes are therefore resistant to most beta lactam antibiotics."

“因此，携带这些基因金黄色葡萄球菌对大多数β-胺抗生素有耐药。”

It's a multidrug resistant bacteria, and it can be treated with cephalosporins, aminoglycosides, fluoroquinolones, and carbapenems in case of beta-lactamase production; only with carbapenems in case of ESBL production; and with colistin, tigecycline or fosfomycin in case of carbapenemases production.

肺炎克雷伯杆菌也是一种多重耐药菌，如果产生β-胺酶，可以用头孢菌素、氨基糖苷类、氟喹诺酮类以及碳青霉烯类药物治疗；如果产生ESBL，可以只应用碳青霉烯类进行治疗；如果产生碳青霉烯酶，则应用多粘菌素、替加环素或磷霉素进行治疗。