And this had happened prior for N-acetylcysteine, NAC, which some people take, it's a mucolytic.

这之前也发生在N-乙酰半（NAC）上，有些人会服用它，它是一种黏液溶解剂，实际上是一种非常有效解充血药。

You would certainly see things like homocysteine drop.

你肯定会看到同型半水平下降。

People have very, very high levels of homocysteine.

人同型半水平非常高。

But as with things like N-acetylcysteine.

但就像N-乙酰半这类事物一样。

And N-acetylcysteine definitely shows on my tests and just subjectively that it bumps NO, nitric oxide.

而且N-乙酰半在我测试中确实显示能提升氮氧化物水平，从主观感受上也是如此。

But I think some people don't like taking N-acetylcysteine chronically?

但我觉得有些人喜欢长期服用N-乙酰半？

But when polyphenols CA and CGA were combined with amino acid cysteines found in milk proteins, their anti-inflammatory effects received a boost.

但当CA和CGA与牛奶蛋白中半结合时，它炎作用得到了强化。

So there's no denying the fact that elevated levels of homocysteine are associated with bad things.

因此，可否认是，高水平同型半与良情况存在关联。

That's unambiguously clear, meaning there's an association between badness and homocysteine.

这一点毋庸置疑地明确，意味着良状况与同型半水平之间存在关联。

Well, things like resveratrol, hydrogen gas, lowering our homocysteine, which for most people is very simple to do.

好吧， 比如白藜芦醇、氢气，降低同型半， 这些对大多数人来说都非常简单。

But mechanistically, homocysteine will inhibit the clearance of something called symmetric and asymmetric dimethyl arginine.

但从机制上讲，同型半会抑制一种名为对称和非对称二甲基精物质清除。

And yeah, of course, they could have used NAC, N-acetylcysteine, which would upregulate glutathione synthesis, but I'm sure it will work.

当然， 他也可以使用NAC，即N-乙酰半， 它能促进谷甘肽合成，但我肯定这会有效。

So this has been proposed as at least one mechanism by which homocysteine might negatively impact vascular disease.

因此，这被提出为同型半可能对血管疾病产生负面影响至少一种机制。

So this is now proposed as a link between what we observe with homocysteine and impaired renal function.

因此，现在有人提出，这可能是我在同型半观察到现象与肾功能受损之间一个联系。

So we know that if you take methylfolate and methyl B12, you're going to lower homocysteine.

因此，我知道，若摄入甲基叶和甲基B12，就能降低同型半水平。这一点是显而易见。

I use an amino acid called trimethylglycine to help people metabolize homocysteine because those microvasculature is very susceptible to high levels of homocysteine.

我使用一种名为三甲基甘基来帮助人代谢同型半，因为那些微血管对高水平同型半非常敏感。

Macrophage cells exposed to polyphenols on their own, for instance, showed more than 2.5 times as much TNF activity as they did in the face of a polyphenols-cysteine adduct.

例如，暴露于多酚中巨噬细胞表现出 TNF 活性是其暴露于多酚-半加合物时 2.5 倍以上。

Um, and again, the, the, the rationale there is, um, I do think there's some evidence that elevated levels of homocysteine are bad in and of themselves.

嗯，再说一遍，其理由在于，我确实认为有证据表明， 同型半水平升高本身就好。

Jacobs was studying whether the TB drug isoniazid was being inactivated by the presence of a particular amino acid, cysteine, which in chemical terms acts as a reducing agent, by donating electrons.

Jacobs 之前一直研究为何肺结核药物异烟肼会被基和半灭活，而异烟肼在化学反应中通过失电子，起到还原剂作用。

And homocysteine impairs their clearance and therefore when you have high levels of homocysteine, it results ultimately in impaired nitric oxide synthase and therefore lower nitric oxide.

同型半会损害它清除能力， 因此当体内同型半水平过高时，最终会导致一氧化氮合酶功能受损， 从而降低一氧化氮生成。