Treatment of essential thrombocythemia depends on risk of blood clots.

发性血小板增多症的治疗取决于血栓形成的风险。

In rare cases, essential thrombocythemia can develop into myelofibrosis and acute leukemia.

少数发性血小板增多症案例会发展为维化或急性白血病。

Hyperaldosteronism can happen due to primary causes which is where the adrenal gland itself is responsible for the excess production of aldosterone.

醛固酮增多症可以是发性的，即肾上腺本身产生了过量的醛固酮。

But more commonly, essential thrombocythemia is usually found unintentionally when elevated platelet levels are found on a routine complete blood count.

发性血小板增多症常常是做常规全血细胞计数时发现血小板增多，而被无意发现的。

Now, some individuals with essential thrombocythemia can have symptoms like fatigue, headache, dizziness, nausea, tinnitus or ringing in the ears, and numbness in the hands and feet.

有些发性血小板增多症的患者，会有疲乏、头痛、晕眩、恶心、耳鸣（耳朵里有声音）以及手足麻木等症状。

The most common primary cause is called idiopathic hyperaldosteronism, because the zona glomerulosa has an increase in the number of cells secreting aldosterone, but it's not really clear why this happens.

最常见的发性病因称为特发性醛固酮增多症：这是由于球状带分泌醛固酮的细胞数量增加，目前尚不清楚为什么会发生这种情况。

All that being said, in situations where somebody produces too much aldosterone, like primary hyperaldosteronism, then there's more potassium secretion by the principal cells and excreted, and therefore less potassium is retained, leading to hypokalemia.

说了这么多，在某人产生了太多醛固酮的情况下，比如发性醛固酮增多症，更多的钾被主细胞分泌并排泄，这意味着更少的钾被保留，导致了低钾血症。