CpG islands are found in most promoter regions of genes which are the DNA sequences responsible for the initiation of gene transcription.

CpG岛位于绝大部分启动子区域，是一组负责转录起始的DNA序列。

In this case, the BCL1 gene from chromosome 11 ends up next to the immunoglobulin promoter on chromosome 14, which again upregulates its expression.

在这种情况下，11体的BCL1基因易位至14体，与14体的蛋白启动子相邻，后者调了BCL1基因的表达。

In eukaryotes, if the introduced genes are derived from another organism, the resulting transgenic plants or animals can be propagated by normal breeding.

转基因羊已经被生产了出来，可以通过它们的奶生产有价值的蛋白。目的基因需要羊的启动子（酪蛋白或乳清蛋白）以确保在乳腺中表达。从奶中纯化蛋白要比从培养的细胞中纯化蛋白要容易的多。

As a result, an the BCL2 gene from chromosome 18 is placed after the immunoglobulin heavy chain promoter on chromosome 14, and that results in overexpression of bcl-2.

因此，一个来自18体的BCL2基因被易位到14体的蛋白重链启动子后，导致BCL-2过表达。

In this case, the Myc gene is translocated from chromosome 8 where it ends up adjacent to IgH promoter on chromosome 14 and again that upregulates its expression.

在这种情况下，MYC基因从8体易位至14体，最终与14体的IgH启动子相邻，这也调了它的表达。