To move goods between Asia and the Mediterranean basin, traders had to traverse the narrow isthmus separating the Red Sea and the Nile, journeying in camel-bound caravans through the unforgiving desert.
The very narrow isthmus of Panama presented a unique opportunity for mankind to build a shortcut by carving a Canal across just a bit more than 50 kilometers worth of land that separated the two oceans here.
This is by far the biggest city that New Zealand has got strategically located along in Isthmus with good natural harbors to the North and the South and placed over a dormant volcanic field with fairly fertile soils.
On February 6 the Nautilus cruised in sight of the city of Aden, perched on a promontory connected to the continent by a narrow isthmus, a sort of inaccessible Gibraltar whose fortifications the English rebuilt after capturing it in 1839.
So Corinth, located on the Gulf of Corinth, occupies a really important strategic place because it's where the Gulf of Corinth is by a small land bridge separating it from the Ionian Sea.
It was the sacred thirst of gold that carried Ovieda, Nicuessa, and Vasco Nugnes de Balboa, to the Isthmus of Darien; that carried Cortes to Mexico, Almagro and Pizarro to Chili and Peru.
As the isthmus was then a part of Colombia, President Roosevelt proceeded to negotiate with the government at Bogota a treaty authorizing the United States to cut a canal through its territory.
Other importations were made, from time to time, by way of the Isthmus, and, though great pains were taken to insure success, about one half usually died on the way.
The latter desert separated advanced human societies of Mesoamerica from those of North America, while the isthmus separated advanced societies of Mesoamerica from those of the Andes and Amazonia.
On January 16, 1939, Matthew W. Sterling took an early morning walk through the wet, buggy forest of Veracruz State, on the Gulf Coast side of Mexico's southern Isthmus.
1939 年 1 月 16 日,马修·斯特林 (Matthew W. Sterling) 清晨在墨西哥南部地峡墨西哥湾沿岸侧的韦拉克鲁斯州潮湿的越野车森林中散步。