From their early, possibly-tree-climbing origins in the Late Eocene or Early Oligocene, they diversified and expanded with the spread of grasslands in the Miocene, taking advantage of new predatory niches.
Were the beautiful volute and cone shells of the Eocene epoch, and the gracefully sculptured ammonites of the Secondary period, created that man might ages afterwards admire them in his cabinet?
Filling ecological niches once occupied by dinosaurs, mammals came to dominate the dry grasslands and forests of the Eocene and beyond, but no species may have been more threatening than humankind.
Back at the start of the Eocene Epoch, the world was in the clutches of the Paleocene-Eocene Thermal Maximum, and warm, damp forests covered the land from pole to pole.
By the start of the Eocene Epoch about 56 million years ago, North America was also home to omomyiforms, a group of tarsier-like primates, and adapiforms, which were more lemur-like.
As they report in Nature, the critter, which lived around 55m years ago, in the Eocene epoch, seems to be the most primitive relative of tarsiers, mouse-sized primates which now inhabit the islands of South-East Asia.
This transition from the Eocene to the Oligocene caused the extinction of 60% of terrestrial mammals around the world, but by the middle Oligocene a new biome emerged that really worked for mustelids - grasslands.