It grates on those who can't handle it themselves.

许多人会觉得和欣赏人生活在一起很困难。

Eustacia looked at the lonely man.

游苔莎望着这个人。

And he wrote suggestions to help people who are lonely.

他还写了一些建议来帮助人。

He holds the record of having been the world's most isolated human.

他保持着世上最人记录。

Well, one possibly lonely man is Mauro Morandi.

嗯，Mauro Morandi 可能是一个人。

Some of the loneliest people spend their entire lives chasing perfection.

有些非常人终其一生都在追求完美。

It sounds like there's a lot of lonely people in this big, massive city.

听起来在这个巨大城市里有很多人。

Those who say they are lonely are likelier to be depressed five years later.

那些说自己人更有可能在五年后抑郁。

They are the best medicine for someone who is lonely, old, or depressed.

是人、老人或是忧郁症患者最佳解药。

But there are times we should stop and look at these isolated people.

但有时我们也该停下脚步 看看这群人。

Many people find it difficult living with someone who likes to be alone.

许多人会觉得和欣赏人生活在一起很困难。

Britain's government has taken a more analytical approach to lonely people.

英国政府对人采取了更为分析方法。

What's worse, how to be a loner?

更糟糕是，如何成为一个人？

Lonely people need a cheering card so they can feel loved.

人需要一张欢呼卡片，这样他们就能感受到爱。

He always says, " Poor Mr. Beethoven. He is a lonely man."

他总是说“可怜贝多芬。他是一个人。”

So when you are a loner, how should you live your life?

那么当你是一个人，你应该如何过你生活呢？

But Thoreau was a loner, a dreamer. Few shared his ideas.

但梭罗是一个人，一个梦想家，所以没有人分享他想法。

There's a man who lives in the Amazon in Brazil called the loneliest man in the world.

有一个住在巴西亚马逊人被称为世上最人。

This could be as simple as calling someone who is alone or greeting a neighbor from your window.

这可以很简单，比如打电话给人或在窗口问候邻居。

Broadly speaking, the genes less active in the lonely were those involved in staving off viral infections.

一般来说，人体内活力较低基因是那些帮助人们避开病毒感染基因。