Even minimal alteration in peplomer integrity through glycoprotein peroxidation could impair attachment to host cellular membranes foiling viral attachment and penetration.
Taking the ecogeographical data into acount, the authors consider the surveyed area to be a natural focus of plague with the marmot M.baibacina as the main rservoir.
After the tolerizing regimen, the host is withdrawn from the suppressive agents, but is able to maintain specific immune tolerance to the immunogenic epitopes present on the toleragen.
Hemaglutinin(HA) is an important absorbent protein and effectiv protective antigen of AIV.It not only mediates AIV to adsorb and penetrate cells,but also makes the host produce immunity against AIV.