T-cells in a patient's immune system are extracted, genetically tweaked to possess " chimeric antigen receptors" (the CARin CAR-T) that can spot these antigens, and then returned to the patient's body.

提取患者免疫系统中的T细胞，对其进行基因改造，使其拥有能够识别这些抗原的“嵌合抗原受体”（CAR-T中的CAR），然后将其送回患者体内。

In 2017 Japanese researchers demonstrated the principle by transplanting parts of a pancreas that had grown inside a mouserat chimera into a diabetic mouse, curing it.

2017年，日本的研究员演示了这个原理。他们把在小鼠-大鼠嵌合体中生长的胰腺的某些部分移植给了一只糖尿病小鼠并治愈了它。

The next most common scenario is mosaicism, meaning the individuals have some cells in their body with the 45, X karyotype and others with a 46, XX karyotype.

另一种最常见的情况是嵌合体，这意味着个体体内的一些细胞具有45，X核型，而另一些细胞具有46，XX核型。

It's a sliding part, and it will stay attached to the box, but have the ability to go back and forth.

滑块始终嵌合在盒体之上不会分离，同可以在滑槽内前后往复滑动。

The rock is densely constructed, thanks to how well its fine-grained crystals and the feldspar interlock.

这种岩石结构致密，得益于其细粒晶体与长石的紧密嵌合。

Fetal microchimerism is where there are fetal DNA or particles in the maternal bloodstream.

胎儿微嵌合现象指的是胎儿的 DNA 或细胞颗粒进入母体血液循环。

The chimera's human cells made their way into all four types of tissue, though they were outnumbered in every case.

嵌合体中的类细胞参与生成了所有四类组织，尽管在每一类中的数量都少于猴子细胞。

The other is the hope that chimeric animals might one day provide a source of organs to be transplanted into sick humans.

另一个希望是有朝一日嵌合动物或许能提供可移植给患者的器官。

Six days after fertilisation these were injected with human extended pluripotent stem cells, which can develop into any other cell type found in the body.

在受精后的第六天向它们注射类扩展多能干细胞（EPSC）。这些干细胞可以发育成嵌合体内的任何其他细胞类型。

The researchers found 126 different sorts of cellto-cell interactions among monkey cells in the chimeric embryos, compared with just 19 in non-chimeric ones, as well as differences in the activity levels of many genes.

研究员发现，嵌合胚胎中的猴子细胞之间有126种不同类型的细胞间相互作用，而在非嵌合体中只有19种。此外许多基因的活性水平也存在差异。

Human cells in the chimera's epiblast behaved more like those found in human embryos than those found in monkey embryos.

嵌合体外胚层中的类细胞的行为更近似于类胚胎细胞，而不像猴子胚胎细胞。

The name comes from Greek mythology, where chimera is an amalgam of three different animals.

这个名字来自希腊神话，其中嵌合体是三种不同动物的混合物。

Could you say that someone is chimeric?

你能说某是嵌合体吗？

Doctors used to think chimeras were extremely rare.

医生过去认为嵌合体极其罕见。

It also includes cancer immunology, which looks at the body's innate ability to prevent or eliminate cancer cells, called immunosurveillance, as well as new treatments like genetically engineered CAR-T cells used to target certain forms of cancer.

它还包括癌症免疫， 研究身体防止或消除癌细胞的先天能力，称为免疫监视， 以及新的治疗方法， 如用于靶向某些类型癌症的基因工程嵌合抗原受体T细胞。

For some researchers, the hope is to harvest human organs from chimeral hybrids to use as transplant donations, but that's still a ways off -- partially because these tests are ethically fraught and highly regulated.

对于一些研究员来说， 希望从嵌合杂交体中收获体器官用作移植捐赠，但这仍然是一个遥远的事情 - 部分原因是这些测试在道德上充满争议并且受到严格监管。

One of countless works it's inspired, including literature like The Hunchback of Notre Dame, which helped motivate extensive renovations that added everything from the chimeras seen today to the spire that fell in 2019.

它是无数作品中的一部， 受到它的启发，包括《巴黎圣母院》等文作品，它推动了大规模的翻修， 增加了从今天看到的嵌合体到 2019 年倒塌的尖塔等一切。

And so it wants to start to kind of get close together and interlock in these, the negative area is happy to be around positive areas and positive happy around.

因此， 它倾向于开始彼此靠近并相互嵌合，负电区域乐于围绕正电区域， 而正电区域也乐于围绕负电区域。

They found that the chimeras had developed with some human cells but not very many of them, and even fewer of them grew to a typical, healthy size.

他们发现嵌合体中有一些细胞，但数量不多，而且其中更少的一部分能长到典型的健康大小。

The result is a chimera, a fantastic fire-breathing creature from Greek mythology, with a lion's head, a goat's body and a serpent's tail.

结果是一个嵌合体， 一种来自希腊神话的奇妙喷火生物，有一个狮子头， 一个山羊的身体和一个蛇的尾巴。