Dopamine itself can't cross the blood-brain barrier, but its precursor levodopa can, and once in the brain, levodopa is converted to dopamine by dopa decarboxylase, most importantly within the remaining nigrostriatal neurons.

多巴本身不能通过脑屏障，但它的前体左旋多巴可以，一旦进入脑中，左旋多巴就会被多巴脱羧酶转换为多巴，尤其是在残存的黑质纹状体神。

Less commonly, babies can have levo-transposition of the great arteries, or l-TGA, with levo meaning that the aorta's primarily to the " left" of the pulmonary artery.

更少见地，宝宝可能会有左旋-大动脉转位，即L-TGA，左旋的意思是主动脉主要位于肺动脉的左侧。

Alright the next dopamine-directed class of therapies are inhibitors of COMT, catecholamine-O-methyltransferase, which is an enzyme that degrades dopamine and levodopa.

下一个针对多巴的治疗药物是COMT抑制剂；COMT，即儿茶酚-O-甲基转移酶，是一种可以降解多巴和左旋多巴的酶。

That suggests the vegan's particular gut flora—adapted to his usual meat-free diet—did not contain species that can digest carnitine.

这表明素食者特殊的肠道菌群――适应了他的无肉饮食――不含有可消化左旋肉碱的种类。

Leads I and aVL, along with two of the chest leads, V5 and V6, are all considered " lateral" leads and they're near the lateral wall of the heart which receives blood from the left circumflex artery.

I、aVL以及V5和V6导联，被认为是“侧壁导联”，因为它们靠近脏的侧壁，这里接受左旋支动脉的液供应。

Experiments in mice confirmed the broader hypothesis: TMAO production relies on microbes that digest carnitine, and prolonged consumption of that chemical by susceptible mice leads to atherosclerosis.

对老鼠进行的实验证实了进一步的猜想：产生TMAO需要能消化左旋肉碱的细菌参与，易患病的老鼠如果长期食用左旋肉碱会导致动脉粥样硬化。

The mismatch in question revolves around a molecule called carnitine.

疑问的焦点集中于一种称为左旋肉碱的分子。

This diet resulted in high levels of both carnitine and TMAO in the volunteers' blood.

该食谱使得志愿者液中的左旋肉碱和TMAO都处在高水平。

The principal difference they found turned out to be levels of L-DOPA.

他们发现的主要差异最终在于左旋多巴的水平。

In most cases, when it comes to that left-hand versus right-hand thing, The molecule cannot just easily go from the left-hand version to the right-hand version.

在大多数情况下， 当涉及到左旋和右旋的问题时，分子不能轻易地从左旋形式转变为右旋形式。

They were randomly assigned to receive either levodopa carbidopa or a matched placebo three times daily for 39 days, along with standardized rehabilitation therapy.

他们被随机分配， 接受为期39天、每日三次的左旋多巴-卡比多巴或匹配的安慰剂治疗，同时配合标准化的康复疗法。

I've responded very well to any sort of like acetylalcarnitine oral form has worked really well for me.

我对任何类型的乙酰左旋肉碱口服制剂都有很好的反应。

They're right–handed with only rare exceptions, and when by chance a shell's spiral is left–handed, collectors will pay its weight in gold for it.

除了极少数例外， 它们都是右旋的，当碰巧贝壳的螺旋是左旋的时，收藏家会花上同等重量的黄金来买它。