Dopamine itself can't cross the blood-brain barrier, but its precursor levodopa can, and once in the brain, levodopa is converted to dopamine by dopa decarboxylase, most importantly within the remaining nigrostriatal neurons.

多巴本身不能通过血脑屏障，但它前体旋多巴可以，一旦进入脑中，旋多巴就会被多巴脱羧酶转换为多巴，尤其是在残存黑质纹状体神经元内。

Less commonly, babies can have levo-transposition of the great arteries, or l-TGA, with levo meaning that the aorta's primarily to the " left" of the pulmonary artery.

更少见地，宝宝可能会有旋-大动转位，即L-TGA，旋意思是主动主要位于肺动侧。

Alright the next dopamine-directed class of therapies are inhibitors of COMT, catecholamine-O-methyltransferase, which is an enzyme that degrades dopamine and levodopa.

下一个针对多巴治疗药物是COMT抑制剂；COMT，即儿茶酚-O-甲基转移酶，是一种可以降解多巴和旋多巴酶。

That suggests the vegan's particular gut flora—adapted to his usual meat-free diet—did not contain species that can digest carnitine.

这表明素食者特殊肠道菌群――适应了他无肉饮食――不含有可消化旋肉碱种类。

Leads I and aVL, along with two of the chest leads, V5 and V6, are all considered " lateral" leads and they're near the lateral wall of the heart which receives blood from the left circumflex artery.

I、aVL以及V5和V6导联，被认为是“侧壁导联”，因为它们靠近心脏侧壁，这里接受旋支动血液供应。

Experiments in mice confirmed the broader hypothesis: TMAO production relies on microbes that digest carnitine, and prolonged consumption of that chemical by susceptible mice leads to atherosclerosis.

对老鼠进行实验证实了进一步猜想：产生TMAO需要能消化旋肉碱细菌参与，易患病老鼠如果长期食用旋肉碱会导致动粥样硬化。

The mismatch in question revolves around a molecule called carnitine.

疑问焦点集中于一种称为旋肉碱分子。

This diet resulted in high levels of both carnitine and TMAO in the volunteers' blood.

该食谱使得志愿者血液中旋肉碱和TMAO都处在高水平。

The principal difference they found turned out to be levels of L-DOPA.

他们发现主要差异最终在于旋多巴水平。

In most cases, when it comes to that left-hand versus right-hand thing, The molecule cannot just easily go from the left-hand version to the right-hand version.

在大多数情况下， 当涉及到旋和右旋问题时，分子不能轻易地从旋形式转变为右旋形式。

They were randomly assigned to receive either levodopa carbidopa or a matched placebo three times daily for 39 days, along with standardized rehabilitation therapy.

他们被随机分配， 接受为期39天、每日三次旋多巴-卡比多巴或匹配安慰剂治疗，同时配合标准化康复疗法。

I've responded very well to any sort of like acetylalcarnitine oral form has worked really well for me.

我对任何类型乙酰旋肉碱口服制剂都有很好反应。

They're right–handed with only rare exceptions, and when by chance a shell's spiral is left–handed, collectors will pay its weight in gold for it.

除了极少数例外， 它们都是右旋，当碰巧贝壳螺旋是旋时，收藏家会花上同等重量黄金来买它。