In this case, eosinophils accumulate in the endocardial layer of the heart tissue, causing inflammation and endocardial fibrosis, making it stiffer and again less compliant.
Ischemia in the areas supplied by the partially occluded vessel illustrated here in the lateral wall of the left ventricle is primarily targeted on the sub endocardial aspect of the affected region.
Whatever the case, the heart needs blood, and if we look at the heart wall, there's three layers—the outermost layer, the epicardium, then the myocardium in the middle, and the endocardium inside the heart.