Etodolac was synthesized with 7-ethyltryptophol and methyl 3-oxopentanoate as the starting materials.Highly pure etodolac was obtained by purifying the crude product with a mixing solvent.
STEP 1 Consider switching from migraine medicine with valproic acid, which can make you eat more, to other migraine medicines that are less likely to increase your appetite, such as sumatriptan.
There is, so far, no cure for isovaleric acidemia, but some treatments — like avoiding foods rich in leucine, and taking supplements of other, non-threatening amino acids — can help keep patients safe.