Hormone replacement therapy, like combined oral contraceptives can be useful for individuals with Turner syndrome, polycystic ovarian syndrome or premature ovarian failure.
In premature ovarian failure when estrogen levels are low the pituitary gland attempts to restore balance by increasing production of gonadotropins LH and FSH.
Most women have a normal puberty with regular periods before the disorder develops, but then start having troubles when premature ovarian failure occurs.
Causes of secondary amenorrhea can also cause primary amenorrhea, and they include functional hypothalamic amenorrhea, polycystic ovary syndrome, hyperprolactinemia, premature ovarian failure and Asherman syndrome.