OBJECTIVE To synthesis 5-bromide benzofuran ketone,the key intermediate of citaopram.

目的合成抗抑郁药西酞普兰中间体5-溴苯酞。

P-Brom-ethylphene was prepared by brom-phene by means of Friedel-Crafts and Huang Ming-long reactions. The synthesis can be industrialized because of good quality, high yield and low cost.

对溴乙苯是以溴苯,经付克乙酰化,黄鸣龙还等应合成,其质量和收率高,成,具有工业化意义。

HPLC method for determination of phenylephrine hydrochloride, paracetamol, caffeine anhydrous,salicylamide and brompheniramine maleate in Liufenkamin tablets was established.

建立了HPLC法测定柳酚咖敏片中盐酸去氧肾上腺素、对乙酰氨基酚、无水咖啡因、水杨酰胺、马来酸溴苯那敏的含量。