As the estrogen is combined with osteoclast, it can inhibit the activity of lysomal enzyme, inhibit bone resorption and decrease the ability of osteclast on forming cavate in bone slice.
With most cases, the macrophage then fuses the phagosome with a lysosome which has hydrolytic enzymes that can pretty much break down any biochemical molecules.
You've got your radiator, ratty, throttle, body rats, mission differ, rats, strats, top rat, thermos rat traction and control, and your lytic converter.