Even opening a single wormhole, kind-of breaks the universe in fundamental ways, potentially creating time travel paradoxes, and violating the causal structure of the universe.
Instead of trying to shield the human body, or rapidly repair damage, we could potentially engineer humans to adopt and express these fungal, melanin-based energy-harvesting systems.
It also is a place where you can potentially harness laws of physics in ways you can't on earth to make products or other things that can't be produced here.