Variolation usually involved rubbing crushed smallpox scabs into cuts on the hand, or blowing them in pellets into the nostrils.

种痘通常包括将碾碎的天花痂粉抹手部的切口中，或将它们作为颗粒吹中。

Variolation probably worked because it introduced  the variola in a part of the body the virus wasn't prepared for, disabling most of its nasty  tricks.

种痘可能有效是因为它将天花毒引毒没有准备好的身体部位，从而它大部分的恶劣手段。

Venetian physician Jacopo Pallarini, who practised variolation in the city, wrote a book about it in 1715. Then British writer Lady Mary Wortley Montagu, who had been left severely disfigured by the disease, observed the practice.

在该城市实践种痘的威尼斯医生雅各波·帕拉里尼于1715年写一本书。随后，英国作家玛丽·沃特利·蒙塔古夫人观察这一做法，她因这种疾而严重毁容。