Breath from Salt by Bijal Trivedi. It's about cystic fibrosis which is a disease that affects over 10,000 kids in the U.S.

《盐的呼吸》作者碧周·翠瓦狄，这是本关于囊性疾病的书，这种疾病影响了美国超过1万名儿童。

Coarse crackles occur when there's pulmonary fibrosis, or scarring in the lungs.

当肺或肺部成时，会出现粗湿啰音。

In rare cases, essential thrombocythemia can develop into myelofibrosis and acute leukemia.

少数原发性血小板增多症案例会发展为骨髓或急性白血病。

They also increase collagen synthesis and fibrosis around the eyes.

它们也会增加眼周胶原成和。

Our friend in Rikers is counting on you.

关在里克岛的那位就指望你了{\an1}{\pos(60，101)}血统：欧洲 身高：183-193厘米 瞳色：蓝色 发色：棕色 需排除的医疗情况： 囊性 遗传性血色沉着。

If fertilization doesn't happen, then the corpus luteum stops making hormones after around 10 days, becomes fibrotic, and is called the corpus albicans.

如果次级卵母细胞没有受精，大概10天之后，黄体就会停止释放激素而，成白体。

Finally, it's worth noting that even folks that don't die from COVID-19 including young and healthy individuals can go on to develop pulmonary fibrosis, a chronic lung condition that can severely impair a person's quality of life.

最后还有一点，即使是那些没有死于COVID-19的患者，包括年轻健康的人，也有可能继续发展成肺；这种慢性肺疾病会严重损害个人生活质量。

When all that stuff stagnates, it initiates an inflammatory reaction that causes macrophages to release inflammatory molecules, which ultimately damage surrounding cells and leads to fibrosis which is the thickening of connective tissue, or the creation of scar tissue.

当所有这些物质淤滞时，将会引发炎症反应，从而导致巨噬细胞释放炎症因子，最终破坏周围细胞，造成组织的，即结缔组织增厚，成瘢组织。

Cystic fibrosis is a genetic disorder that causes scarring of the pancreas, while pulmonary fibrosis is a scarring of the lungs, resulting in shortness of breath.

囊肿性是一种会在胰腺上产生伤的遗传疾病，而肺则是在肺上产生伤从而成呼吸困难。

Initially these inflammatory changes are completely reversible, but over the years irreversible changes start to take place —edema, scarring, and fibrosis build up, leading to thickening of the epithelial basement membrane, which permanently reduces the airway diameter.

最初这些炎症变是完全可逆的，但是随时间进展，不可逆的变开始发生，出现水肿、瘢、等症状，导致上皮基底膜增厚，从而永久性地减小气道直径。

One or more of these could move toward trials in the next few years, says Riley, including one for multi-resistant tuberculosis and another for pulmonary infections in cystic fibrosis patients.

赖利说，其中一种或多种药物有望在未来几年进入临床试验阶段，其中一种用于治疗耐多药结核病，另一种用于治疗囊性患者的肺部感染。

The treatment, which counteracts the effects of a genetic mutation carried by 90% of Cystic fibrosis patients, comes 30 years after researchers identified the gene behind the disease.

在研究人员确定该疾病背后的基因30年后，该疗法抵消了90%的囊性患者所携带的基因突变的影响。

We are finding mucus is compromised in a number of diseases or conditions, including inflammatory bowel disease, cystic fibrosis, certain forms of dental cavity formation, certain forms of infertility.

我们发现，黏液在多种疾病或状况中受到损害，包括炎症性肠病、囊性、某些式的龋齿成以及某些式的不孕。

Editing the unhealthy cells of those suffering from genetic diseases such as Duchenne's muscular dystrophy and cystic fibrosis will alleviate their suffering.

编辑那些患有杜氏肌营养不良和囊性等遗传疾病的人的不健康细胞将减轻患者痛苦。

The variation present in most non-Africans with cystic fibrosis is responsible for only about 30% of cases in people of African origin.

基因突变引起的囊性是大多数非非洲人心力衰竭的原因，因这一遗传原因发病的非洲人只有30%。

Our first season is about a pathologist named Dorothy Andersen, the first person to identify cystic fibrosis in a patient in the 1930s.

我们第一级介绍的是病理学家 Dorothy Andersen，她在上世纪30年代首次在患者中发现囊细胞。

Alright, as a quick recap, cirrhosis is when inflammation and liver damage causes the liver to become fibrotic and develop scar tissue.

得！快速总结一下：肝硬是指由炎症和肝脏损伤导致肝脏，并成瘢组织。

The tissue that's encapsulated by the granuloma undergoes fibrosis and often calcification, producing scar tissue that can be seen on x-ray

被肉芽肿包裹的组织会且会钙，成瘢组织，这种钙组织可以在X光片上看到。

But when proteins fold in the wrong way that can lead to everything from allergies to cystic fibrosis and Tay-Sachs disease.

但是，当蛋白质以错误的方式折叠时，会导致从过敏到囊性和泰-萨克斯病等各种疾病。

Chronic vesicoureteral reflux can cause pyelonephritis, or inflammation of the kidney, and renal scarring, or fibrosis which damages the kidney tissue.

慢性膀胱输尿管反流可能导致肾盂肾炎，即肾脏出现炎症反应，以及瘢肾，即肾组织因而受损。