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Colistin is active against most strains of gram negative bacteria including P. aeruginosa, E. coli, K. pneumoniae, Aerobacter.

多粘极反对株革兰氏阴包括绿脓,大肺炎克雷伯 , 产气。

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Osmosis-微生物

So, with Klebsiella, urease makes urea dissociate into carbon dioxide and ammonia.

肺炎克雷伯杆菌产生的脲酶使得素分解成碳和氨。

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Osmosis-微生物

Finally, Klebsiella pneumoniae grows well on MacConkey agar, which is a medium that contains a pH sensitive dye and lactose.

最后,肺炎克雷伯杆菌可以在含有pH指示剂的MacConkey琼脂培养基上良好地生长。

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Osmosis-微生物

Klebsiella pneumoniae can normally colonize the oropharynx and the gastrointestinal tract.

正常情况下,肺炎克雷伯杆菌是人体口咽与胃肠道的定植菌。

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Osmosis-微生物

Klebsiella pneumoniae is a multidrug resistant bacterium, which produces different enzymes that break down the structure of antibiotics.

肺炎克雷伯杆菌是一种多重耐药菌,它能产生多种分解抗生素的酶。

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Osmosis-微生物

For diagnosis, Klebsiella pneumoniae can be isolated in cultures from blood, sputum, or urine depending on the type of infection.

根据感染类型,从血、痰或者分离出肺炎克雷伯杆菌,即可诊断。

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Osmosis-微生物

Alright, now Klebsiella pneumoniae is urease positive, which means it can produce an enzyme called urease that dissociates urea into carbon dioxide and ammonia.

肺炎克雷伯杆菌脲酶阳性,可以产生脲酶,将素分解成碳和氨。

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Osmosis-微生物

Now, Klebsiella pneumoniae has a number of virulence factors that are like assault weaponry that help it attack and destroy the host cells and evade the immune system.

肺炎克雷伯杆菌具有多种毒力,可以攻击宿主细胞,并逃避免疫。

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Osmosis-微生物

Now, Klebsiella pneumoniae can cause various hospital-acquired infections in people with underlying illnesses (like diabetes) and in the presence of foreign devices like central venous catheters, endotracheal tubes, or urinary catheters.

同时,肺炎克雷伯杆菌容易在患有基础疾病(如糖病)的人群和应用心静脉导管、气管内插管或者导管的人群,引起各种医院获得性感染。

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Osmosis-微生物

It's a multidrug resistant bacteria, and it can be treated with cephalosporins, aminoglycosides, fluoroquinolones, and carbapenems in case of beta-lactamase production; only with carbapenems in case of ESBL production; and with colistin, tigecycline or fosfomycin in case of carbapenemases production.

肺炎克雷伯杆菌也是一种多重耐药菌,如果产生β-内酰胺酶,可以用头孢菌素、氨基糖苷类、氟喹诺酮类以及碳青霉烯类药物治疗;如果产生ESBL,可以只应用碳青霉烯类进行治疗;如果产生碳青霉烯酶,则应用多粘菌素、替加环素或磷霉素进行治疗。

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