Non-toxic inhibitor for esterase, lipase and N-formyl-methionine aminopeptidase. Inhibits also carboxypeptidase Y-like exopeptidase.
酯酶、脂肪酶和N-甲酰甲硫酸肽酶无毒的抑制剂。也抑制羧肽酶Y类外肽酶。
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The researchers also found that the enrichment of the peptidase in the host's body will significantly reduce the clinical efficacy of Sitagliptin, a commonly used diabetes treatment medication, as Sitagliptin cannot inhibit the activity of DPP4 effectively.
研究人员还发现,宿主体内肽酶的富集显著降低常用糖尿病治疗药物西格列汀的临床疗效,因为西格列汀不能有效抑制 DPP4 的活性。