Renin also causes constriction of blood vessels which helps raise blood pressure.

肾素也能引起血管收缩，从而帮助升高血压。

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

另一个例子是肿瘤的生长也会产生过多的醛，一种类似于肾素的物质，会液体的积存。

Along the same lines, drugs that reduce the effect of aldosterone can also cause hyperkalemia, and these are drugs like renin inhibitors, ACE inhibitors, angiotensin II receptor antagonists, selective aldosterone blockers, and potassium-sparing diuretics.

同理，可降低醛效能的药物也可高血症，例如肾素抑制剂、ACE抑制剂、血管紧张素II受体拮抗剂、选择性醛受体阻滞剂及保利尿剂等。

In primary hyperaldosteronism, the main problem is that zona glomerulosa cells secrete high levels of aldosterone, and that aldosterone has a negative feedback effect on renin, and so it actually inhibits renin production.

在原发性醛增多症中，主要问题是球状带细胞分泌高水平的醛；醛肾素有负反馈作用，因而实际上抑制肾素生成。

Your kidneys cook up hormones like renin and angiotensin which help regulate levels of sodium and fluids in your body, and also help expand and constrict blood vessels.

你的肾脏会分泌肾素和血管紧张素等荷尔蒙，这些荷尔蒙有助于调节体内钠和液体的水平，也有助于扩张和收缩血管。

Another study shows that when salt intake drops below 1.5 teaspoons per day, a significant increase in renin and aldosterone occurs.

另一项研究显示，当盐摄入量降至每天 1.5 茶匙下，人体中的醛及肾素水平将大幅上升。

In chronic kidney disease, the falling glomerular filtration rate leads to more and more renin secretion which leads to hypertension.

慢性肾病中，GFR降低，更多肾素分泌，进而引发高血压。

The juxtaglomerular cells then receive the signal and also independently sense the low pressure in the blood vessels and secrete an enzyme called renin which increases sodium reabsorption which helps raise the blood volume.

球旁细胞接收信号，同时也可感受血管低血压，并分泌一种叫肾素的酶，而肾素能增加钠的重吸收，从而能增加血容量。

When not enough blood flows to the kidneys, the kidney secretes the hormone renin, which ultimately helps the kidneys retain more water.

当肾脏中的血流不充足时，肾脏就会分泌肾素，帮助肾脏留存住更多的水。

Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

醛属于一特定激素家族或激素轴的一部分，这些激素共同作用，被称为肾素-血管紧张素-醛系统。

When there is less sodium, the body increases activity in the renin-angiotensin-aldosterone system or the RAAS.

当体内钠含量较少时，人体 RAA 系统（肾素血管紧张素醛系统）开始活跃。

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

醛增多症的诊断主要通过测定肾素与醛的水平来完成。

For example, normally when the kidneys start sensing a lower than normal amount of fluid getting filtered, they respond by releasing the hormone renin to increase the blood pressure.

例如，通常肾在感知到滤过量减少时会释放肾素作为应答，升高血压。

So in this case aldosterone levels are high and renin levels are low in.

因此，在这种情况下，醛水平较高，肾素水平较低。

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

醛增多症的继发性原因通常是由于高水平肾素醛生成过多。

Aldosterone is secreted in response to elevated levels of renin, and it's role is to bind to receptors on two types of cells along the distal convoluted tubule of the nephron.

肾素水平升高可刺激醛的分泌，后者的作用是结合肾远曲小管中两种细胞上的受体。

Angiotensin recruits aldosterone to reabsorb salt and water, which adds volume to the blood.

肾素-血管紧张素系统会招募醛重吸收盐和水，从而增加血容量。

And the ratio as such, it's typically to screen quote-unquote positive is about 20 for aldosterone ring-in ratio, but for LC-MS, it will be like 15.

这个比率通常用于筛查所谓的阳性， 即醛与肾素比值约为20，但使用液相色谱-质谱法时， 这一数值会降至15。

Once it senses a change it secretes a hormone (called renin) which leads to a message being sent to the two switches.

一旦它感知到变化，就会分泌一种激素（称为肾素），这会一个信息被发送到两个开关。