Renin also causes constriction of blood vessels which helps raise blood pressure.

也能引起血管收缩，从而帮助升高血压。

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

另一个例子是肿瘤的生长也会产生过多的醛固酮，一种类似于的物质，会导致液体的积存。

Along the same lines, drugs that reduce the effect of aldosterone can also cause hyperkalemia, and these are drugs like renin inhibitors, ACE inhibitors, angiotensin II receptor antagonists, selective aldosterone blockers, and potassium-sparing diuretics.

同，可以降低醛固酮效能的药物也可以导致高血症，例如抑制剂、ACE抑制剂、血管紧张II受体拮抗剂、选择性醛固酮受体阻滞剂以及保利尿剂等。

In primary hyperaldosteronism, the main problem is that zona glomerulosa cells secrete high levels of aldosterone, and that aldosterone has a negative feedback effect on renin, and so it actually inhibits renin production.

在原发性醛固酮增多症中，主要问题是球状带细胞分泌高水平的醛固酮；醛固酮对有负反馈作用，因而实际上抑制生成。

Your kidneys cook up hormones like renin and angiotensin which help regulate levels of sodium and fluids in your body, and also help expand and constrict blood vessels.

你的脏会分泌和血管紧张等荷尔蒙，这些荷尔蒙有助于调节体内钠和液体的水平，也有助于扩张和收缩血管。

Another study shows that when salt intake drops below 1.5 teaspoons per day, a significant increase in renin and aldosterone occurs.

另一项研究显，当盐摄入量降至每天 1.5 茶匙以下，人体中的醛固酮及水平将大幅上升。

In chronic kidney disease, the falling glomerular filtration rate leads to more and more renin secretion which leads to hypertension.

慢性病中，GFR降低，导致更多分泌，进而引发高血压。

The juxtaglomerular cells then receive the signal and also independently sense the low pressure in the blood vessels and secrete an enzyme called renin which increases sodium reabsorption which helps raise the blood volume.

球旁细胞接收信号，同时也可感受血管低血压，并分泌一种叫的酶，而能增加钠的重吸收，从而能增加血容量。

When not enough blood flows to the kidneys, the kidney secretes the hormone renin, which ultimately helps the kidneys retain more water.

当脏中的血流不充足时，脏就会分泌，以帮助脏留存住更多的水。

Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

醛固酮属于一特定激家族或激轴的一部分，这些激共同作用，被称为-血管紧张-醛固酮系统。

When there is less sodium, the body increases activity in the renin-angiotensin-aldosterone system or the RAAS.

当体内钠含量较少时，人体 RAA 系统（血管紧张醛固酮系统）开始活跃。

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

醛固酮增多症的诊断主要通过测定与醛固酮的水平来完成。

For example, normally when the kidneys start sensing a lower than normal amount of fluid getting filtered, they respond by releasing the hormone renin to increase the blood pressure.

例如，通常在感知到滤过量减少时会释放作为应答，升高血压。

So in this case aldosterone levels are high and renin levels are low in.

因此，在这种情况下，醛固酮水平较高，水平较低。

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

醛固酮增多症的继发性原因通常是由于高水平导致醛固酮生成过多。

Aldosterone is secreted in response to elevated levels of renin, and it's role is to bind to receptors on two types of cells along the distal convoluted tubule of the nephron.

水平升高可刺激醛固酮的分泌，后者的作用是结合远曲小管中两种细胞上的受体。

Angiotensin recruits aldosterone to reabsorb salt and water, which adds volume to the blood.

-血管紧张系统会招募醛固酮以重吸收盐和水，从而增加血容量。

And the ratio as such, it's typically to screen quote-unquote positive is about 20 for aldosterone ring-in ratio, but for LC-MS, it will be like 15.

这个比率通常用于筛查所谓的阳性， 即醛固酮与比值约为20，但使用液相色谱-质谱法时， 这一数值会降至15。

Once it senses a change it secretes a hormone (called renin) which leads to a message being sent to the two switches.

一旦它感知到变化，就会分泌一种激（称为），这会导致一个信息被发送到两个开关。