And this had happened prior for N-acetylcysteine, NAC, which some people take, it's a mucolytic.

这之前也发生在N-乙酰半胱氨酸（NAC）上，有些人服用它，它是一种黏液溶解剂，实际上是一种非常有效的解充血药。

You would certainly see things like homocysteine drop.

你肯定同型半胱氨酸水平下降。

People have very, very high levels of homocysteine.

人们的同型半胱氨酸水平非常高。

But as with things like N-acetylcysteine.

但就像N-乙酰半胱氨酸这类事物一样。

And N-acetylcysteine definitely shows on my tests and just subjectively that it bumps NO, nitric oxide.

而且N-乙酰半胱氨酸在我的测试中实显示能提升氮氧化物的水平，从主观感受上也是如此。

But I think some people don't like taking N-acetylcysteine chronically?

但我觉得有些人喜欢长期服用N-乙酰半胱氨酸？

But when polyphenols CA and CGA were combined with amino acid cysteines found in milk proteins, their anti-inflammatory effects received a boost.

但当CA和CGA与牛奶蛋白中的半胱氨酸结合时，它们的抗炎作用得了强化。

So there's no denying the fact that elevated levels of homocysteine are associated with bad things.

因此，可否认的是，高水平的同型半胱氨酸与良情况存在关联。

That's unambiguously clear, meaning there's an association between badness and homocysteine.

这一点毋庸置疑地明，着良状况与同型半胱氨酸水平之间存在关联。

Well, things like resveratrol, hydrogen gas, lowering our homocysteine, which for most people is very simple to do.

好吧， 比如白藜芦醇、氢气，降低同型半胱氨酸， 这些对大多数人来说都非常简单。

But mechanistically, homocysteine will inhibit the clearance of something called symmetric and asymmetric dimethyl arginine.

但从机制上讲，同型半胱氨酸抑制一种名为对称和非对称二甲基精氨酸的物质的清除。

And yeah, of course, they could have used NAC, N-acetylcysteine, which would upregulate glutathione synthesis, but I'm sure it will work.

当然， 他们也可以使用NAC，即N-乙酰半胱氨酸， 它能促进谷胱甘肽的合成，但我肯定这有效。

So this has been proposed as at least one mechanism by which homocysteine might negatively impact vascular disease.

因此，这被提出为同型半胱氨酸可能对血管疾病产生负面影响至少一种机制。

So this is now proposed as a link between what we observe with homocysteine and impaired renal function.

因此，现在有人提出，这可能是我们在同型半胱氨酸观察的现象与肾功能受损之间的一个联系。

So we know that if you take methylfolate and methyl B12, you're going to lower homocysteine.

因此，我们知道，若摄入甲基叶酸和甲基B12，就能降低同型半胱氨酸水平。这一点是显而易见的。

I use an amino acid called trimethylglycine to help people metabolize homocysteine because those microvasculature is very susceptible to high levels of homocysteine.

我使用一种名为三甲基甘氨酸的氨基酸来帮助人们代谢同型半胱氨酸，因为那些微血管对高水平的同型半胱氨酸非常敏感。

Macrophage cells exposed to polyphenols on their own, for instance, showed more than 2.5 times as much TNF activity as they did in the face of a polyphenols-cysteine adduct.

例如，暴露于多酚中的巨噬细胞表现出的 TNF 活性是其暴露于多酚-半胱氨酸加合物时的 2.5 倍以上。

Um, and again, the, the, the rationale there is, um, I do think there's some evidence that elevated levels of homocysteine are bad in and of themselves.

嗯，再说一遍，其理由在于，我实认为有证据表明， 同型半胱氨酸水平升高本身就好。

Jacobs was studying whether the TB drug isoniazid was being inactivated by the presence of a particular amino acid, cysteine, which in chemical terms acts as a reducing agent, by donating electrons.

Jacobs 之前一直研究为何肺结核药物异烟肼被氨基酸和半胱氨酸灭活，而异烟肼在化学反应中通过失电子，起还原剂的作用。

And homocysteine impairs their clearance and therefore when you have high levels of homocysteine, it results ultimately in impaired nitric oxide synthase and therefore lower nitric oxide.

同型半胱氨酸损害它们的清除能力， 因此当体内同型半胱氨酸水平过高时，最终导致一氧化氮合酶功能受损， 从而降低一氧化氮的生成。