METHODS Terazosin hydrochloride was synthesized from anhydro-piperazine via acylation,reduction,amination,salification etc.

方法以无水哌嗪为起始原料,经酰、还原、、等反应制得酸特拉唑嗪。

The title resin has been prepared by Friedel-Crafts acylation followed by bromination and amination.The method avoids the utilization of cancerogenic chloromethyl methyl ether.

通酰基反应引入乙酰基，接着溴、，得到标题树脂。该法避免了使用氯甲醚。