Some experts assert that this work signifies a paradigm shift in antibiotic discovery.

些专家断言，这项工作标志着抗生素现的范式转变。

This is the argument brought up to challenge this change of paradigm.

这是为挑战这种范式的变化而提出的论点。

The ever-evolving illicit drug trade is shifting to a new paradigm.

不断演化的非法毒品贸易正转变为种新范式。

In this paradigm, as he explains, there were clear causalities, certainties.

正如他所解释的那样，这种范式中，有明确的因果关系和确定性。

The transition from one paradigm to another won't happen overnight.

从种范式到另种范式的转变不夜之间生。

The evidence makes clear it is time for a paradigm shift on testing.

据清楚地表明，是时候转变测试范式了。

A research paradigm consists of three elements; ontology, epistemology, and methodology.

研究范式包括三个要素：本体论、认识论和方法论。

The group that represents producers of television and movies said the agreement " represents a new paradigm."

代表电视和电影制片人的组织表示，这项协议“代表了种新的范式”。

This behavioral change is perhaps unsurprising when it's intentional, the result of domestication and a controlled breeding paradigm.

当这种行为变化是驯养和控制繁殖范式的结果时，它是有意的，也许并不令人惊讶。

We need more resources, but very little change actually in practice came about. And then there was a paradigm.

更多的资源 但是实际上生的变化很少 然后出现了种范式。

But, in management-speak, there's been a paradigm shift.

但是，管理方面，已经生了范式转变。

This may be the point where we get that paradigm to change a little bit.

这可能是我们让范式稍微改变的地方。

This is the beginning of a new paradigm in medicine.

这是医学新范式的开始。

There is multitrillion dollars to be made from paradigm shifts.

从范式转变中可赚取数万亿美元。

And much like the case we just did, here's kind of very basic paradigm.

就像我们刚才做的案例样，这是个非常基本的范式。

You must take conscious control over the paradigm, remove and replace it.

你必须有意识地控制这个范式， 移除并替换它。

So please think of these as signposts, approaches, paradigms that give some science for satisfaction.

所以请把这些视为路标、方法、范式，它们能为满足感提供些科学依据。

So, what can each of the three sociological paradigms tell us about sexuality?

那么，每个社学范式能告诉我们关于性的些什么信息呢？

The success of the Sony TR-55 caused a paradigm shift in the West.

索尼TR-55的成功引起了西方的场范式转移。

The Apollo guidance computer was the first computer to use them----a huge paradigm shift.

阿波罗导航计算机是第台使用它们的计算机——这是个巨大的范式转移。