Objective: To evaluate the safety and efficacy of combining deferiprone(DFP)and deferoxamine(DFO)in iron chelation therapy in patients with thalassemia.
Characters : Sequesters minerals which can interfere with soil removal or react with alkaline builders. Prevents yellowing or graying caused by soil redeposit.
In this paper, the new chelating resin (PSIM) with a polythioether backbone bearing imidazole group is first synthesized by the reaction between polychloromethylthiirane and imidazole.
3, A chelating agent which forms an easily water-soluble metal chelated compound such as nitrilotriacetate (NTA) or ethylene diamine tetraacetate (EDTA) is incorporated in a detergent composition.
Another cytokine called IL-10 mediates the expression of increased ferritin receptors on the surface of macrophages, which then sequesters even more iron.
Lead poisoning has also been shown to denature enzymes important in heme synthesis, like Delta aminolevulinate dehydratase and ferrochelatase, which are important for heme synthesis.
Finally, it needs iron to thrive and replicate, so it produces a siderophore, which is a term used for a group of small, high-affinity, iron chelating compounds that snatch iron from host cells.