Those antibodies also activate the complement pathway which leads to muscle cell destruction.

些抗也会激活补通路，破坏肌肉细胞。

The complement system is a family of small proteins that work in an enzymatic cascade to fight off bacterial infections.

补系统是一群小的蛋白质，以酶促级联的方式抵抗细菌感染。

Rituximab is a monoclonal antibody that binds CD20 and induces complement-mediated lysis, as well as direct cytotoxicity and apoptosis.

利妥昔单抗是一种单克隆抗，与CD20结合，诱导补介导的分解作用，以及直接的细胞毒性和凋亡。

Anti-Ro antibody Test 3) Complement (C3 and C5) level test, as their levels go down when lupus is more active.

抗 Ro 抗测试 3) 补（C3 和 C5）水平测试，因为当狼疮更加活跃时， 它们的水平会下降。

The activation of complement causes inflammation and destruction of the muscle cells and reduces the amount of acetylcholine receptors on the surface.

补激活引起炎症反应，破坏肌肉细胞，减少其表面的乙酰胆碱受数量。

As the antibody- antigen complex circulates in the blood, the complex " fixes" complement to it.

结果是，补激活了强活性的酶的产生，穿透了细菌细胞壁，并使细菌有机破裂。

Sometimes an antibody hooks to a bacterial antigen but needs an intermediate, or complement, to actually destroy the bacterium.

当抗抗原复合物在血液循环中运行时，该结合会与补结合。

Now, LPS has the ability to avoid complement-mediated killing by inhibiting the formation of the membrane attack complex and preventing membrane damage and bacterial cell death.

LPS可以通过抑制膜攻击复合物（MAC）的形成，逃避补介导的杀伤作用，防止细胞膜损伤和细菌死亡。

And on immunofluorescence, there might be nonspecific focal deposits of IgM and complement proteins, and these get trapped in the areas of hyalinosis, but these isn't always seen.

在免疫荧光电镜下，可能有非特异性病灶IgM和补蛋白沉积；些沉积局限于玻璃样变区域，但不总是出现。

When the abnormal IgA1-IgG immune complexes deposit in the mesangium, the alternative complement pathway is activated, leading to the release of proinflammatory cytokines and migration of macrophages into the kidney, all of which contributes to glomerular injury.

当异常的IgA1-IgG免疫复合物沉积在系膜上时，补旁路途径被激活，导致促炎因子的释放，同时促进巨噬细胞向肾迁移，以上所有反应会导致肾小球的损伤。