The clinicopathologic features and family history are compatible with epidermolytic palmoplantar keratoderma.

临床病理表现及家族史都符合掌蹠表皮松解性症的诊断。

Treatment: milium, syringgoma, xanthoma of eyelid, benignpapilloma, sudoriceratosis, facial explosive powder thesaurismosis,helosis, leucoderma, acne rosacea, and encapsulated acne,etc.

9、治疗：栗、管瘤、睑黄瘤、良性乳头状瘤、管症、爆炸伤异物（爆炸粒沉着症）、鸡眼、胼底、白癜风、酒渣鼻、包裹性刺等。

Dyskeratosis congenita (DKC) is a rare inherited disease characterized by the triad of abnormal skin pigmentation, nail dystrophy, and mucosal leukoplakia.

先天性良症（DKC）为一少见之遗传性疾病，三项主要特徵为皮肤色素异常、 指甲生长异常及黏膜白斑症。

This paper is reported a rare case of palmoplanter keratoma hereditaria-keratoma hereditaria mutilans and differential diagnosis with various palmoplantar keratodermas and dactylolysis are discussed.

本文报告了一例罕见的遗传性掌跖皮肤病—遗传性残毁性瘤,并与各种掌跖皮肤症、断肢症的鉴别进行了讨论。