One type of medication is an acetylcholinesterase inhibitor, like neostigmine or pyridostigmine.

其中一种药物是乙酰胆（AChE）抑制剂，如新斯的明或吡斯的明。

The team of doctors who have examined Navalny since his arrival on Saturday had found the presence of " cholinesterase inhibitors" in his system, the statement said.

这份声明指出，自纳瓦尔尼周六抵达德国以来，医生团队对他进行了检查，发现他体内存" 胆抑制剂" 。

Sarin kills by bonding with Acetylcholineserase, completely changing it's physical structure.

沙林通过与乙酰胆结合，彻底改变其物理结构来致人死亡。

And sure, there's a lot of animal literature showing, for instance, that there's a disruption in certain enzymatic pathways within neurons, in particular, and this is the one that intrigues me the most, a disruption in what's called acetylcholine esterase.

当然，有很多物研究表明，例如，神经元内的某些促途径中存，特别是对所谓的乙酰胆的，这一点最让我感兴趣。

1993 Tacrine is the first cholinesterase inhibitor drug for Alzheimer's, but is withdrawn from general use in 2013 due to safety concerns.

1993年， Tacrine是第一种用于阿尔茨海默病的胆抑制剂药物，但由于安全问题， 它2013年被停止通用。

So, let's talk about these for a minute starting with cholinesterase inhibitors.

所以，让我们先从胆抑制剂开始谈一分钟。

When your brain tells the muscles to stop contracting, the acetylcholine has to be removed, this is done with Acetylcholinesterase an enzyme that breaks down the acetylcholine into its constituent parts allowing your muscles to relax.

当你的大脑告诉肌肉停止收缩时，乙酰胆就必须被移除， 这是由乙酰胆这种来完成的， 它会将乙酰胆分解成其组成部分， 从而使你的肌肉得以放松。

And indeed, there's a fair amount of evidence showing that microplastics and nanoplastics are correlated with reductions

确实，有相当多的证据表明微塑料和纳米塑料与乙酰胆活性的降低有关。

Now, since Alzheimer's has been linked to a deficiency of acetylcholine in the brain, cholinesterase inhibitors were introduced to alleviate the symptoms of the disease.

现，由于老年痴呆症与大脑中乙酰胆缺乏有关，胆抑制剂被用来减轻这种疾病的症状。

Or just changes in acetylcholine esterase activity.

或仅是乙酰胆活性的变化。

As their name suggests, cholinesterase inhibitors work simply by inhibiting cholinesterase enzymes from breaking down acetylcholine, thereby increasing both the level and duration of action of acetylcholine.

顾名思义，胆抑制剂只是通过抑制胆而起作用从分解乙酰胆，从而增加水平和持续时间乙酰胆的作用。

It's important to note here that out of the three, Rivastigmine is the only one that shows significant inhibition of both acetylcholinesterase and butyrylcholinesterase.

值得注意的是，这三种药物中，利瓦斯蒂明是唯一对乙酰胆和丁酰胆均有明显的抑制作用。