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Objective To evaluate the clinical and biochemical features of patients with aldosteronoma in adrenal incidentaloma.

目的分析肾上腺意外患者的临床及生化特征。

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Osmosis-泌尿

An important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

肾脏中种帮助调节钾重吸收或分泌的重要激素叫

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Osmosis-泌尿

Other pathological conditions that cause increased aldosterone levels include compensated heart failure and cirrhosis.

其他导水平增加的病理状况包括代偿期心衰和肝硬化。

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Osmosis-分泌

With these medications around, aldosterone can't exert its effects.

有了这些药物,就无法发挥其作用了。

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Osmosis-心血管

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

个例子是肿瘤的生长也会产生过多的种类似于肾素的物质,会导的积存。

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When there is less sodium, the body increases activity in the renin-angiotensin-aldosterone system or the RAAS.

含量较少时,人 RAA 系统(肾素血管紧张素系统)开始活跃。

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Osmosis-分泌

Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

属于特定激素家族或激素轴的部分,这些激素共同作用,被称为肾素-血管紧张素-系统。

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Osmosis-泌尿

Now, an important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

所以,肾脏中有种重要的激素可以帮助调节钾的重吸收和分泌,这就是

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Aldosterone has it's purpose, but it's not a hormone you want to regularly have high levels of.

有其作用,但在人中,这种荷尔蒙的水平不能太高。

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Osmosis-分泌

Hyperaldosteronism can also be due to secondary causes where the pathology lies outside of the adrenal gland.

增多症也可以是继发性的,即病变位于肾上腺以外。

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As this study shows, a low salt diet increases aldosterone by more than 3 fold in healthy people.

这项研究显示,健康正常人采用低盐饮食,其水平将增加 3 倍有余。

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Osmosis-分泌

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

增多症的继发性原因通常是由于高水平肾素导生成过多。

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This suggests that people actually following the WHO guidelines are chronically raising their aldosterone.

也就是说,遵循世卫组织关于盐摄入量建议的人们,他们长期处于较高水平。

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Osmosis-分泌

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

增多症的诊断主要通过测定肾素与的水平来完成。

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Osmosis-分泌

So in this case aldosterone levels are high and renin levels are low in.

因此,在这种情况下,水平较高,肾素水平较低。

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High aldosterone is associated with increased inflammation, Chronic kidney disease, Osteoporosis, and cardiovascular disease.

水平会增加炎症,导慢性肾病、骨质疏松症以及心血管疾病。

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Osmosis-分泌

Hyperaldosteronism can happen due to primary causes which is where the adrenal gland itself is responsible for the excess production of aldosterone.

增多症可以是原发性的,即肾上腺本身产生了过量的

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In particular, it's implicated in oxidative stress and myocardial fibrosis — an abnormal thickening of the heart valves.

与氧化应激和心肌纤维化(心脏瓣膜异常增厚)尤其相关。

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These drugs inhibit Angiotensin Converting Enzyme, hindering an important step in the RAA system resulting in lower aldosterone and lower blood pressure.

这种药物通过抑制血管紧张素转化酶的作用(RAA 系统的关键作用之),以达到降低水平及血压的目的。

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Another study shows that when salt intake drops below 1.5 teaspoons per day, a significant increase in renin and aldosterone occurs.

项研究显示,当盐摄入量降至每天 1.5 茶匙以下,人中的及肾素水平将大幅上升。

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On the flip side of aldosterone, there is a group of hormones called natriuretic hormones, i. e. sodium urinating hormones.

的另面,有组激素叫利激素,也就是尿荷尔蒙。

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