The sympathetic neurons releases norepinephrine, also called noradrenaline, and the cells of the adrenal medulla release norepinephrine and epinephrine, also called adrenaline.
Alright, as a quick recap, neuroblastoma is a condition where neural crest cells of the developing sympathetic nervous system and adrenal medulla do not differentiate normally.
In the lumbar region, neural crest cells differentiate into the cells of the adrenal medulla, the inner part of the adrenal gland that sits atop the kidneys.
The remaining filtrate passes from the PCT into the loop of Henle, which starts in the cortex, then dips into the medulla before coming back into the cortex.