A recombinant HGP44 inhibited HIV-1 replication at a 50% effective concentration of approximately 2.5 micromolar, the researchers note, somewhat less potently than did P. gingivalis extracts.
重组HGP44蛋白酶在约2.5微克分子的50%有效浓度时能抑制HIV-1复制,然而重组HGP44比直接从牙卟啉菌中提取的有效性略低。