allopurinol

Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

论早期诊断并及时给予嘌呤醇及静脉碱化利尿是治疗TLS的关键。

If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。