bioactivation

Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究表明线粒乙醛脱酶是化硝酸甘油生物转化的主要途径，线粒乙醛脱酶同时具有脱酶和酯酶的化活，其酯酶活通过将硝酸甘油脱硝形成一氧化氮，进而血管扩张。