bioactivation

Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究粒体乙醛脱酶是体内催化酸甘油生物转化的主要途径，粒体乙醛脱酶同时具有脱酶和酯酶的催化活性，其酯酶活性可以通过将酸甘油脱一氧化氮，进而血管扩张。