胺化

METHODS Terazosin hydrochloride was synthesized from anhydro-piperazine via acylation,reduction,amination,salification etc.

方法以无水哌嗪为起始原料,经酰化、还原、胺化、成盐等反应制得盐酸特拉唑嗪。

The title resin has been prepared by Friedel-Crafts acylation followed by bromination and amination.The method avoids the utilization of cancerogenic chloromethyl methyl ether.

通过付氏酰基化反应引入乙酰基，着溴化、胺化，得到标题树脂。该法避免了使用氯甲醚。