GABA is metabolized by the successive action of GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH), to succinic acid, which is a substrate for the tricarboxylic acid cycle.
GABA的降解主要由GABA转氨酶(GABA-T)催化,脱氨基成琥珀半醛,再经琥珀半醛脱氢酶(SSADH)催化成琥珀,进入三羧循环。