GABA is metabolized by the successive action of GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH), to succinic acid, which is a substrate for the tricarboxylic acid cycle.
GABA的降解主要由GABA转氨(GABA-T),氨基生成琥珀酸半醛,再经琥珀酸半醛氢(SSADH)生成琥珀酸,进入三羧酸循环。