It receives dopaminergic innervations from ventral tegment area and SNc, and noradrenergic and serotonergic innervations from the locus ceruleus (LC) and dorsal raphe nucleus (DRN), respectively.
侧前额叶皮层主要接受来自侧被盖区(ventral tegmental area,VTA)和SNc的DA能神经纤维投射,来自蓝斑的去甲肾腺素(noradrenaline,NA)能和中缝背核的5-HT能神经纤维投射。