It receives dopaminergic innervations from ventral tegment area and SNc, and noradrenergic and serotonergic innervations from the locus ceruleus (LC) and dorsal raphe nucleus (DRN), respectively.
内前额叶皮层主要接受来自盖区(ventral tegmental area,VTA)SNc的DA能神经纤维投射,以来自蓝斑的去甲肾上腺素(noradrenaline,NA)能背核的5-HT能神经纤维投射。