N-phosphoryl amino acids could be catalyzed by imidazole to result in solvolysis such as ester exchanges on phosphorus, esterification, formation of peptides and N→O migration of the phosphoryl group.
唑对磷酰化氨基的活化反应具有较强的催化作用,磷酰化丝、苏氨唑催化不仅能剂解反应,如磷上酯交换、羧基活化成酯、成肽及磷酰基的N→O迁移等,而且还会分子内环化反应;