N-phosphoryl amino acids could be catalyzed by imidazole to result in solvolysis such as ester exchanges on phosphorus, esterification, formation of peptides and N→O migration of the phosphoryl group.
咪唑对磷酰氨基酸的活反应具有较强的催,磷酰丝、苏氨酸在咪唑催不仅能发生溶剂解反应,如磷换、羧基活成、成肽及磷酰基的N→O迁移等,而且还会发生分子内环反应;