Cyanopyridine,intermediate of rimifon, was synthesized from 4-picoline using vanadium oxide as a catalyst in a fixed-bed reactor, reached 99% conversion of 4-picoline, 88% selectivity and 87.
以4甲基吡啶原料,在固定床反应器中通过含氧钒的催生气固相接触氨氧反应制备雷封中间体4氰基吡啶,4甲基吡啶的转99%,4氰基吡啶的选择性88%,收87。