氰基吡啶

Cyanopyridine,intermediate of rimifon, was synthesized from 4-picoline using vanadium oxide as a catalyst in a fixed-bed reactor, reached 99% conversion of 4-picoline, 88% selectivity and 87.

以4甲基吡为原料,在固定床反应器中通过钒催剂发生气固相接触氨反应制备雷封中间体4氰基吡,4甲基吡转率为99%,4氰基吡择性为88%,收率为87。