It's linked to global warming, acid rain, effects on wildlife, depletion of the ozone layer.

空气污染和全球变暖、酸雨、野生动保护、臭氧层耗竭这些问题息息相关。

The massive formation of clots throughout the body depletes the supply of platelets and clotting factors.

全身血凝块的大量形成耗竭了血小板和凝血因子。

Other, even more severe, fatal complications can come from depleted electrolytes and water in the blood.

严重的致命并发症可能来自血液中电解质和水分的耗竭。

This original study on ego depletion was published in 1998 by a psychologist called Roy Baumeister.

关自我耗竭的这项原始研究是由心理学家罗伊·鲍迈斯特 1998 年发表的。

And this came out of some research done several years ago now around this concept called Ego Depletion.

这个观点源几年前关一种叫做" 自我耗竭" 的概念的研究。

After I cared for individuals with autism, young people, I experienced an emotional burnout.

在我照顾了患有自闭症的年轻人们之后，我经历了情绪耗竭。

Past interventions have successfully helped depleted fish populations recover.

过去的干预措施已成功帮助耗竭的鱼类种群恢复。

The other, nutrient depletion in the center of the rings from heightened competition with plants.

另一种则是由间加剧的竞争导致环中心养分耗竭。

We'll hit on the unique T cell situation first, why being exhausted is actually key.

我们先来讨论一下T细胞的独特状况，为什么耗竭状态实际上至关重要。

Today, we're tackling a really critical bottleneck in modern medicine, T-cell exhaustion.

如今，我们正面对现代医学中一个极为关键的瓶颈问题——T细胞耗竭。

It's like how Amazon has 14 codified leadership rules that lead to high productivity, but a lot of burnout and competition.

就比如亚马逊有14条成文的领导规则，这些规则能带来高生产率，但也会带来耗竭和竞争。

The second component is emotional exhaustion.

第二个组成部分是情绪耗竭。

How can exhausted cells possibly lead to a good response to immunotherapy?

耗竭的细胞如何可能带来对免疫治疗的良好反应？

The proteotoxic stress response specific to exhausted T cells.

特异性针对耗竭T细胞的蛋白质毒性应激反应。

But we probably need to do it with less arable land because, unfortunately, cropland is being depleted.

但我们可能需要用少的耕地来实现这一目标，因为不幸的是， 农田正在逐渐耗竭。

And this is very important, because virgin plastic is made from fossil fuels that are an exhaustible resource.

这一点非常重要，因为原生塑料是由可耗竭资源的化石燃料制成的。

So this is going to be like, I think, an emotionally draining experience for the people in the stands.

所以，我认为这将会是场让现场观众情感耗竭的体验。

The cycle left me emotionally exhausted and anxious as I worked hard to be a stable, attuned, peaceful parent.

这段循环让我情绪耗竭，焦虑不安，因为我要努力做一个稳定、敏感、平和的父母。

Then they saw declining TLSs, and finally, late stage or exhausted TLSs, where the functional signals were very low.

随后，们观察到TLSs数量减少，最终出现晚期或耗竭状态的TLSs，功能信号极低。

And emotionally exhaustion is something that I think a lot of people that experience stress identify with.

而情绪耗竭是许多经历压力的人能够感同身受的一种情况。