Cyanopyridine,intermediate of rimifon, was synthesized from 4-picoline using vanadium oxide as a catalyst in a fixed-bed reactor, reached 99% conversion of 4-picoline, 88% selectivity and 87.

以4甲基吡啶为原料,在定床反应器中氧化钒的化剂发生接触氨氧化反应制备雷米封中间体4氰基吡啶,4甲基吡啶的转化率为99%,4氰基吡啶的选择性为88%,收率为87。