重大

This was the greatest event in the annals of European integration.

这是欧洲统一史上最重大的事件。

The important events at the beginning of the century provided the backdrop for his novel.

本世纪初的一些重大事件为他的小说背景。

His accession to the important post was a big event.

他就任这一重要职务是一个重大事件。

Heads of state are confronted with making decisions of great moment.

国家元首们面临作出具有重大意义的决定。

This is a significant contribution to knowledge.

这是对知识的重大贡献。

The brigadier was cashiered for his big mistake.

旅长因犯重大错误而被职。

Important changes are already in the pipeline.

重大的变已在酝酿之中。

She knew wherein her gross defects lay.

她知道自己的重大缺点在哪里。

It is a discovery that made medical history.

这是载入医学史册的重大发现。

It was easy to believe that the tiny hamlet held some great mystery.

很容易让人相信这个小村庄藏着重大谜团。

He incurred a heavy loss through you.

他因为你而遭受重大损失。

The inferences drawn from data have led to some major changes in our policy.

根做出的推论使得我们的方针发生一些重大变化。

Doctors are making great inroads in the fight against cancer.

在抗癌的战斗中医生正取得重大进展。

This event is so important that we should inscroll it into the annals.

这一事件太重大，我们应该把它写进史册。

The invention of the wheel was a milestone in the history of the world.

发明轮子是世界历史上的重大事件。

It's the big moment in my life.

这是我一生中的重大时刻。

They agreed as to the grand outlines,but quibbled over particulars.

他们对重大要点表示同意,但对细节却含糊其词。

Both the farmers and fishermen were hard hit by the bad weather.

坏天气使农民和渔民都遭受重大损失。

In what sense was the discovery of America a focal point in history?

从什么意义上讲美洲的发现是历史上的一个重大事件呢？

It was a fruitful meeting; we made a lot of important decisions.

这是一次很有成效的会议, 我们做出许多重大决定。