重大的

This was the greatest event in the annals of European integration.

这欧洲统一史上最大事件。

The important events at the beginning of the century provided the backdrop for his novel.

本世纪初一些大事件为他小说提供了背景。

Heads of state are confronted with making decisions of great moment.

国家元首们面临作出具有大意义决定。

This is a significant contribution to knowledge.

这对知识大贡献。

Important changes are already in the pipeline.

大变革已在酝酿之中。

She knew wherein her gross defects lay.

她知道自己大缺点在哪里。

It is a discovery that made medical history.

这载入医学史大发。

The invention of the wheel was a milestone in the history of the world.

发明世界历史上大事件。

It's the big moment in my life.

这我一生中大时刻。

In what sense was the discovery of America a focal point in history?

从什么意义上讲美洲发历史上一个大事件呢？

With the establishment of major new markets, the economy is thriving.

随着大新市场建立，经济越来越兴旺。

Penicillin was acclaimed as the most important discovery during the 1940's.

青霉素曾被公认二十世纪四十年代最大发。

The present aspect of society is portentous of great change.

在社会预示着大变革发生。

The Government's decision is a real kick in the teeth for the unions.

政府决定对工会大打击。

This is a book that displays the considerable scholarship of its author.

这一本表作者大学术成就书。

Scientists say these unmanned flights can make important and exciting discoveries.

科学家们说这次无人驾驶太空飞行能够获得令人兴奋大发。

Her wedding was the event of the year.

她婚礼那一年大事件。

They were understood to have reviewed all major foreign policy issues.

据了解, 他们讨论了所有大外交政策问题。

Through similar and supplementary action , polygenes can have important effects on total variability.

通过相同和添加作用，多基因可以对总变异起大影响。

The registry holds records of all major operations.

登记处有所有大手术记录。