effector

1.NK cell will trigger effector functions(cytolysis) by KAR,if target cell loses appropriate ligands recognized by KIR.

如果靶失去KIR所识别的配体，NK即可通过KAR对靶行攻击。

2.In addition, only certain murine mAb isotypes hae been shown to effectiely bind to and actiate elements of the human immune system, thereby triggering cytotoxic effector functions10.

另外，只有某些亚型的鼠单抗可以有效的结合并激活人免疫系统，以激发毒作用[10]。