intoxication

1.He began to drink, drank himself to intoxication, till he slept obliterated.

他一直喝, 喝到他快要迷糊地睡着了。

2."Mr.Heath Ledger died as the result of acute intoxication by the combined effects of oxycodone, hydrocodone, diazepam, temazepam, alprazolam, and doxylamine," the office said in a short statement.

主要意思是已经定论征判断死亡是意外，由于处方药引起混合效应中毒。